Invitrogen™ FEN1 Monoclonal Antibody (A1B12)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA542534

Product Code. 17719153

Description

Positive Control: MCF-7 cell lysate, K562 cell lysate, Daudi cell lysate, PC-12 cell lysate, NIH/3T3 cell lysate, human tonsil tissue, human liver carcinoma tissue, human breast carcinoma tissue, K562. Subcellular Location: Nucleolus, nucleoplasm. Mitochondrion.

FEN-1 (Flap Endonuclease and Five prime Exonuclease) is a 42 a protein that functions as an endonuclease that cleaves branched DNA structures containing single-stranded 5' flaps or as an exonuclease on DNA nicks and gaps. FEN-1 endonuclease and exonuclease activities are stimulated by an association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to have important roles in DNA replication and repair and is required in cell-free DNA replication systems.

Specifications

• Antigen: FEN1
• Classification: Monoclonal
• Concentration: 2 mg/mL
• Formulation: TBS with 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P39748, P39749, Q5XIP6
• Gene Symbols: FEN1
• Immunogen: Recombinant protein within human FEN1 aa 150-380.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: A1B12
• Conjugate: Unconjugated
• Gene: FEN1
• Gene Alias: AW538437; DNase IV; fen1; FEN-1; fen1 {ECO:0000255; FEN-1 {ECO:0000255; Flap endonuclease 1; flap endonuclease 1 {ECO:0000255; flap structure specific endonuclease 1; flap structure-specific endonuclease 1; flap structure-specific endonuclease 1 {ECO:0000255; HAMAP-Rule:MF_03140}; hFEN-1; Maturation factor 1; maturation factor-1; MF1; RAD2
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 14156, 2237, 84490
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid