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Invitrogen™ FDFT1 Monoclonal Antibody (24GB5645)

Description
FDFT1 Monoclonal Antibody for Western Blot
FDFT1 catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.
Specifications
Specifications
| Antigen | FDFT1 |
| Applications | Flow Cytometry, Western Blot, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | 24GB5645 |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | FDFT1 |
| Gene Accession No. | P37268 |
| Gene Alias | DGPT; EGK_18680; ERG9; farnesyl diphosphate farnesyl transferase 1; farnesyl diphosphate farnesyltransferase; farnesyl-diphosphate farnesyltransferase; farnesyl-diphosphate farnesyltransferase 1; FDFT1; FPP:FPP farnesyltransferase; presqualene-di-diphosphate synthase; SQS; Squalene synthase; squalene synthetase; SS |
| Gene Symbols | FDFT1 |
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Product Title
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