FDC Mouse anti-Human, Clone: CNA.42, eBioscience™

Mouse Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9968-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg

Disclaimers: For Research Use Only.

Product Code. 15298287

Quantity Price
1 £ 54.42 / 25µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification


Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Format Purified
Regulatory Status RUO
Applications Flow Cytometry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunohistochemistry (Frozen)
Applications Western Blotting
Clone CNA.42
Host Species Mouse
Primary or Secondary Primary
Antigen FDC
Gene Alias Follicular dendritic cell
Isotype IgM
Conjugate Unlabeled
Species Reactivity Human
Monoclonal or Polyclonal Monoclonal
Quantity 25μg
Concentration 0.5mg/mL
Storage Requirements Store at 2-8°C.

The monoclonal antibody CNA.42 recognizes a unique carbohydrate epitope found on follicular dendritic cells (FDCs) from a variety of species. FDCs are large cells in germinal centers (GCs) of primary and lymphoid tissues. They present non-processed antigen and switch off apoptosis of B cells through a selection process resulting in selection of memory B cells. FDCs express many B cell markers such as CD21 (long isoform), CD23 and CD35. A role for FDCs as been shown in various infectious diseases such as AIDS and transmissible spongiform encephalitis. Staining with this CNA.42 monoclonal antibody is mainly restricted to the plasma membrane but in limited cases may also be cytoplasmic (as seen in mast cells).

This monoclonal has been shown to be a useful reagent for both flow cytometry and IHC analysis.