Invitrogen™ FCRLA Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA530731

Product Code. 13495237

Description

Recommended positive controls: Raji. Predicted reactivity: Human (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Receptors for the Fc fragment of IgG, or FCGRs (see MIM 146790), are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. All FCGR genes map to human chromosome 1. Additional genes in this region, including FREB, encode FCGR homologs that are selectively expressed in B cells and may be implicated in B-cell development and lymphomagenesis.

Specifications

• Antigen: FCRLA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FCRLA
• Gene Alias: Fc receptor homolog expressed in B cells (FREB); fc receptor homolog expressed in B-cells; Fc receptor like A; Fc receptor related protein X; Fc receptor-like A; Fc receptor-like and mucin-like 1; fc receptor-like and mucin-like protein 1; Fc receptor-like protein; fc receptor-related protein X; FCRL; FCRL1; FCRLA; FCRLb; FCRLc1; FCRLc2; FCRLd; FCRLe; FCRLM1; FCRLX; FCRX; FREB; UNQ291/PRO329
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84824
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q7L513
• Gene Symbols: FCRLA
• Immunogen: Recombinant protein encompassing a sequence within the center region of human FCRLM1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG