FCGR3A Mouse anti-Human, PE, Clone: COC16, Abnova™

Mouse monoclonal antibody raised against human FCGR3A.

Brand:  Abnova MAB12395.50Reactions

Product Code. 16178779

Description

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

• Antigen: FCGR3A
• Classification: Monoclonal
• Conjugate: PE
• Dilution: Flow cytometry Immunofluorescence The optimal working dilution should be determined by the end user.
• Gene Alias: CD16/CD16A/FCG3/FCGR3/FCGRIII/FCR-10/FCRIII/FCRIIIA/IGFR3
• Host Species: Mouse
• Purification Method: Protein A/G affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2214
• Content And Storage: Store at 4°C. Do not freeze.
• Isotype: IgG1

• Applications: Flow Cytometry, Immunofluorescence
• Clone: COC16
• Description: Mouse monoclonal antibody raised against human FCGR3A.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide, 0.2% BSA)
• Gene Symbols: FCGR3A
• Immunogen: FCGR3A
• Quantity: 50 Reactions
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid