Fcμ Receptor Mouse anti-Mouse, PE, Clone: MM3, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 566030

Product Code. 15834699

Description

The MM3 monoclonal antibody specifically binds to the Fc receptor for IgM (Fcμ Receptor, FcμR), which is also known as Fas apoptosis inhibitory molecule 3 (Faim3) or Toso. The Fcμ Receptor is a transmembrane sialoglycoprotein that is encoded by Fcmr (Fc fragment of IgM receptor). This receptor contains an extracellular Ig-like domain that is homologous to two other IgM-binding receptors, the Fc receptor for IgM and polymeric IgA (Fc /μR) and the polymeric Ig receptor (pIgR). Unlike these receptors, the Fcμ Receptor exhibits exclusive binding specificity for the Fc region of IgM. Fcμ Receptor expression is restricted to B lymphocytes. Although expressed by all mature B cell subsets, Fcμ Receptor levels are transiently downregulated by germinal center B cells. This receptor is not expressed by T cells, NK cells, dendritic cells, or myeloid cells.

R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae. It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule. This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.

Specifications

• Antigen: Fcμ Receptor
• Clone: MM3
• Conjugate: PE
• Gene Alias: Fcmr, FcmuR, Fcμ Receptor, FcμR, Faim3, Toso
• Immunogen: Mouse FcμR Transfected Cell Line
• Quantity: 50 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Mouse
• Isotype: IgG1 κ