Invitrogen™ FBXW8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA544382

Product Code. 15526482

Description

Peptide sequence: MNQKLWEVYS GHPVQHISFS SHSLITANVP YQTVMRNADL DSFTTHRRHR Sequence homology: Cow: 83%; Dog: 92%; Guinea Pig: 83%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 92%.

This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Specifications

• Antigen: FBXW8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FBXW8
• Gene Alias: 4930438M06Rik; F-box and WD repeat domain containing 8; F-box and WD-40 domain protein 8; F-box and WD-40 domain-containing protein 8; F-box only protein 29; F-box protein FBX29; F-box/WD repeat-containing protein 8; FBW6; FBW8; Fbx29; FBXO29; FBXW6; FBXW8; LOW QUALITY PROTEIN: F-box/WD repeat-containing protein 8; MGC33534
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26259
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8N3Y1
• Gene Symbols: FBXW8
• Immunogen: Synthetic peptide directed towards the middle region of human FBXW8.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG