Invitrogen™ FBXO8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5114038

Product Code. 17181894

Description

Immunogen sequence: EFFRHIHAPE ERGEYLETLI TKFSHRFCAC NPDLMRELGL SPDAVYVLCY For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.

Specifications

• Antigen: FBXO8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Fbxo8
• Gene Alias: DC10; F-box only protein 8; F-box protein 8; F-box protein Fbx8; F-box/SEC7 protein FBS; FBS; Fbx8; FBXO8; UNQ1877/PRO4320
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26269
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9NRD0
• Gene Symbols: Fbxo8
• Immunogen: Synthetic peptide directed towards the middle region of human FBXO8.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG