missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ Fasudil hydrochloride

Tocris Bioscience™ Fasudil hydrochloride
GREENER_CHOICE

Product Code. 18094052
Change view
Click to view available options
Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
18094052 10 mg 10mg
18073882 50 mg 50mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Product Code. 18094052 Supplier Tocris Bioscience™ Supplier No. 0541/10

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Inhibitor of cyclic nucleotide dependent- and Rho-kinases

Fasudil hydrochloride is a cyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor (IC50 = 10.7 μM). Fasudil suppresses MMP-2 expression and induces apoptosis in glioblastoma cells in vivo. Fasudil is a Ca2+ antagonist, vasodilator and inhibits proliferation of vascular smooth muscle cells. Fasudil binds to α-synuclein to reduce aggregate formation in cellular models of Parkinson's disease, also displays neuroprotective properties and increases survival of dopaminergic neurons in vivo.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 105628-07-7
Molecular Formula C14H18ClN3O2S

Specifications

Quantity 10 mg
Formula Weight 327.83
Purity >98%
Molecular Weight (g/mol) 327.827
Chemical Name or Material Fasudil hydrochloride
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.