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Fasudil Hydrochloride, MedChemExpress

Product Code. 16430976
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Product Code. 16430976 Supplier Medchem Express Supplier No. HY10341

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Description

MedChemExpress Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil Hydrochloride is also a potent Ca2+ channel antagonist and vasodilator.

Fasudil (HA-1077

Specifications

Chemical Name or Material Fasudil Hydrochloride
CAS 105628-07-7
Color White
Purity Grade Notes Research
Molecular Formula C14H18ClN3O2S
Quantity 200 mg
Synonym HA-1077 HydrochlorideAT-877 Hydrochloride
Solubility Information H2O : 55 mg/mL (167.77 mM; Need ultrasonic) ∣DMSO : ≥ 31 mg/mL (94.56 mM)
SMILES O=S(C1=CC=CC2=C1C=CN=C2)(N3CCNCCC3)=O.Cl[H]
Molecular Weight (g/mol) 327.83
Formula Weight 327.83
Percent Purity 95.0%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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