Invitrogen™ FANCL Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5115212

Product Code. 17277973

Description

Antibody detects endogenous levels of total FANCL.

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms.

Specifications

• Antigen: FANCL
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FANCL
• Gene Alias: 2010322C19Rik; AW554273; B230118H11Rik; E3 ubiquitin-protein ligase FANCL; FA complementation group L; FAAP43; FANCL; Fanconi anemia complementation group L; fanconi anemia group L protein; Fanconi anemia group L protein homolog; Fanconi anemia, complementation group L; fanconi anemia-associated polypeptide of 43 kDa; FLJ10335; gcd; germ cell deficient; PHD finger protein 9; Phf9; Pog; proliferation of germ cells protein; RING-type E3 ubiquitin transferase FANCL
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 305600, 55120, 67030
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9CR14, Q9NW38
• Gene Symbols: FANCL
• Immunogen: A synthesized peptide derived from human FANCL(Accession Q9NW38), corresponding to amino acid residues P262-A312.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG