Invitrogen™ FAN Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA554707

Product Code. 15702641

Description

Immunogen sequence: FELDVPGKVE DVVETLLQLH RASCLDKLGD QTAMITAILQ SRLARTSFDK NRFQNISEKL HMECKAE Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 91%.

This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: FAN
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NSMAF
• Gene Alias: AA959567; C630007J05; factor associated with neutral sphingomyelinase activation; Factor associated with N-SMase activation; FAN; GRAMD5; neutral sphingomyelinase (N-SMase) activation associated factor; neutral sphingomyelinase activation associated factor; NSMAF; Protein FAN
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8439
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q92636
• Gene Symbols: NSMAF
• Immunogen: Recombinant protein corresponding to Human FAN. Recombinant protein control fragment (Product #RP-93731).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG