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Description
Immunogen sequence: FELDVPGKVE DVVETLLQLH RASCLDKLGD QTAMITAILQ SRLARTSFDK NRFQNISEKL HMECKAE Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 91%.
This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.
Specifications
Specifications
| Antigen | FAN |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.4 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | NSMAF |
| Gene Accession No. | Q92636 |
| Gene Alias | AA959567; C630007J05; factor associated with neutral sphingomyelinase activation; Factor associated with N-SMase activation; FAN; GRAMD5; neutral sphingomyelinase (N-SMase) activation associated factor; neutral sphingomyelinase activation associated factor; NSMAF; Protein FAN |
| Gene Symbols | NSMAF |
| Show More |
Product Title
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