Invitrogen™ FAM62B Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5109710

Product Code. 17127643

Description

Immunogen sequence: EKRERPPDHQ HSAQVKRPSV SKEGRKTSIK SHMSGSPGPG GSNTAPSTPV IGGSDKPGME EKAQPPEAGP QGLHDLGRSS SSLLASPGHI SVKEPTPSIA SDISLPIATQ ELRQRLRQLE NGTTLGQSPL G.

Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS) (PubMed:27044890). [UniProt].

Specifications

• Antigen: FAM62B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ESYT2
• Gene Alias: 2410017M09Rik; 4921504I16Rik; chr2 synaptotagmin; CHR2SYT; D12Ertd551e; ESYT2; E-Syt2; extended synaptotagmin 2; extended synaptotagmin like protein 2; extended synaptotagmin protein 2; extended synaptotagmin-2; extended synaptotagmin-like protein 2; Fam62b; family with sequence similarity 62 (C2 domain containing), member B; family with sequence similarity 62, member B; KIAA1228; RGD1565705
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 52635, 57488
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.1 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: A0FGR8, Q3TZZ7
• Gene Symbols: ESYT2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 630-760 of human FAM62B (NP_065779.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG