Invitrogen™ WDR5 Recombinant Human Monoclonal Antibody (RAB-C223)

Human Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA551835

Product Code. 30089204

Description

This antibody recognizes WDR5 (WD repeat-containing protein 5). It binds to a folded domain, amino acids 1-334. WDR5 is a protein that is involved in histone modification.

Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.

Specifications

• Antigen: WDR5
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Gene Accession No.: P61964
• Gene Symbols: WDR5
• Immunogen: This antibody was obtained by recombinant antibody (rAb) phage display recognizing WDR5 protein under non-denaturing conditions.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: F(ab) κ

• Applications: ChIP Assay, ELISA, Flow Cytometry, Immunoprecipitation, Immunocytochemistry, Mass Spectrometry
• Clone: RAB-C223
• Conjugate: Unconjugated
• Gene: WDR5
• Gene Alias: 2410008O07Rik; AA408785; AA960360; Big; BIG3; BIG-3; BMP2-induced 3-kb gene protein; CFAP89; cilia and flagella associated protein 89; SWD3; SWD3, Set1c WD40 repeat protein, homolog; Unknown (protein for MGC:137327); WD repeat domain 5; WD repeat-containing protein 5; WD repeat-containing protein BIG-3; Wdr5; wu:fk47f04; zgc:56591; zgc:76895; zgc:76895 protein
• Host Species: Human
• Purification Method: Metal-chelate chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11091
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid