FAM149B1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA558687

Product Code. 15766561

Description

Immunogen sequence: ERDSTIFGIR GKKLHFSSSY AHKASSIAKS SSFCSMERDE EDSIIVSEGI IEEYLAFDHI DIEEG Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 71%.

Involved in cilium assembly and protein localization to cilium. Predicted to be located in cilium. Implicated in Joubert syndrome. FAM149B1 (Family With Sequence Similarity 149 Member B1) is a Protein Coding gene. Diseases associated with FAM149B1 include Joubert Syndrome 36 and Orofaciodigital Syndrome Vi. An important paralog of this gene is FAM149A. Involved in the localization of proteins to the cilium and cilium assembly. Indirectly regulates the signaling functions of the cilium, being required for normal SHH/smoothened signaling and proper development.

Specifications

• Antigen: FAM149B1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FAM149B1
• Gene Alias: FAM149B1; family with sequence similarity 149 member B1; family with sequence similarity 149, member B1; KIAA0974; Protein FAM149B1; RGD1359592
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 317662
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96BN6
• Gene Symbols: FAM149B1
• Immunogen: Recombinant protein corresponding to Human FAM149B1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Research Use Only