Invitrogen™ FAM111A Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA558827

Product Code. 15726701

Description

Immunogen sequence: RSRKHSVNEK CNMKIEHYFS PVSKEQQNNC STSLMRMESR GDPRATTNTQ AQRFHSPKKN PEDQTMPQNR TIYVTLKVNH RRNQDMKL Highest antigen sequence identity to the following orthologs: Mouse - 45%, Rat - 47%.

With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and isconsidered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene isimportant for regulation ofcellcycle arrest and apoptosisfollowing double strand DNA breaks. Atmmutation leadsto the disorderknown as ataxia telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitzsyndrome are also associatedwith defectsin chromosome 11. The FAM111A gene product has been provisionally designated FAM111A pending furthercharacterization.

Specifications

• Antigen: FAM111A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FAM111A
• Gene Alias: 4632417K18Rik; AW413625; Fam111a; family with sequence similarity 111 member A; family with sequence similarity 111, member A; GCLEB; KCS2; Kiaa1895; Protein FAM111A; RGD1560913
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 63901
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.5 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96PZ2
• Gene Symbols: FAM111A
• Immunogen: Recombinant protein corresponding to Human FAM111A. Recombinant protein control fragment (Product #RP-97448).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG