Factor X/Xa Polyclonal Antibody, Invitrogen™

Sheep Polyclonal Antibody

Brand:  Invitrogen PA143047

Product Code. 11518830

Description

PA1-43047 detects Factor X in human samples. PA1-43047 has successfully been used in Western blot and ELISA applications. PA1-43047 was derived from human factor X.

Factor X undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.

Specifications

• Antigen: Factor X/Xa
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: F10
• Gene Alias: Activated factor Xa heavy chain; blood coagulation factor X; Cf10; coagulation factor 10; coagulation factor X; coagulation factor X protein; F10; Factor X heavy chain; Factor X light chain; factor Xa; FX; FXA; prothrombinase; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product
• Host Species: Sheep
• Purification Method: Ammonium sulfate precipitation, Ion-exchange chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2159
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 15.2 mg/mL
• Formulation: 50% water with 50% glycerol and no preservative
• Gene Accession No.: P00742
• Gene Symbols: F10
• Immunogen: Human Factor X.
• Quantity: 1 mg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG