Invitrogen™ Factor VII Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA547475

Product Code. 15597962

Description

In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) Factor VII, rhFactor X, and rhFactor Xa is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 production can cause coagulopathy.

Specifications

• Antigen: Factor VII
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: F7
• Gene Alias: AI132620; Cf7; Coagulation factor VII; coagulation factor VII (serum prothrombin conversion accelerator); eptacog alfa; F7; Factor 7; Factor VII heavy chain; Factor VII light chain; Factor7; FVII; FVII coagulation protein; proconvertin; Serum prothrombin conversion accelerator; SPCA
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14068
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P70375
• Gene Symbols: F7
• Immunogen: CHO-derived recombinant mouse Coagulation Factor VII Ala42-Leu446.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG