Invitrogen™ Factor V Monoclonal Antibody (5146)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA143005

Product Code. 11539852

Description

MA1-43005 detects Factor V in human samples. MA1-43005 has successfully been used in Western blot and ELISA applications. MA1-43005 was derived from human factor V and the heavy chain (fragment D, 94,000) of factor Va.

Coagulation factor V (or Proaccelerin) is an essential factor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The active factor V is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in the Factor V gene can result various diseases including Factor V deficiency, thrombophilia due to activated protein C resistance, Budd-Chiari syndrome, Ischemic stroke, and recurrent pregnancy loss.

Specifications

• Antigen: Factor V
• Classification: Monoclonal
• Concentration: 9.2 mg/mL
• Formulation: 50% water with 50% glycerol and no preservative
• Gene Accession No.: P12259
• Gene Symbols: F5
• Immunogen: Human factor V and heavy chain of factor Va.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 5146
• Conjugate: Unconjugated
• Gene: F5
• Gene Alias: Ac2-120; Activated protein C cofactor; AI173222; Cf5; Cf-5; coagulation factor V; coagulation factor V (proaccelerin, labile factor); Coagulation factor V heavy chain; coagulation factor V jinjiang A2 domain; Coagulation factor V light chain; F5; Factor 5; factor V; factor V Leiden; Factor5; FVL; PCCF; Proaccelerin, labile factor; RPRGL1; THPH2
• Host Species: Mouse
• Purification Method: SDS-PAGE
• Regulatory Status: RUO
• Gene ID (Entrez): 2153
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid