Invitrogen™ FABP5 Monoclonal Antibody (311215)

Rat Monoclonal Antibody

Brand:  Invitrogen™ MA524029

Product Code. 15523722

Description

In direct ELISAs and Western blots, no cross-reactivity with recombinant human FABP1, 2, 3, 4, 6, 7, or 9 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

FABP5 (fatty acid binding protein 5 (psoriasis-associated)) is a proteinthat in humans is encoded by theFABP5 gene, also known as PAFABP, EFABP, E-FABP, KFABP, PA-FABP, Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog. It is a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. The PAFABP cDNA encodes a 135-amino acid protein with molecular weight 15,164. This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated inpsoriasistissue. It is though that FABPs roles include fatty acid uptake, transport, and metabolism. Kaczocha et al. (2009) identifiedFABP5and FABP7 as cytosolic proteins that transport AEA from the plasma membrane to subcellular fatty acid amide hydrolase, where it is hydrolyzed and inactivated. FABP3 did not show this specific transport function.

Specifications

• Antigen: FABP5
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q01469
• Gene Symbols: Fabp5
• Immunogen: E. coli-derived recombinant human FABP5/E-FABP Ala2-Glu135.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 311215
• Conjugate: Unconjugated
• Gene: Fabp5
• Gene Alias: C-FABP; Cutaneous fatty acid-binding protein; DA11; EFABP; E-FABP; E-FABPPAFABP; Epidermal-type fatty acid-binding protein; epithelial fatty acid-binding protein; Fabp5; Fabpe; fatty acid binding protein 5; fatty acid binding protein 5 (psoriasis-associated); fatty acid binding protein 5, epidermal; fatty acid-binding protein 5; Fatty acid-binding protein, epidermal; fatty acid-binding protein, epidermal; uncharacterized protein LOC16592; keratinocyte lipid-binding protein; KFABP; Klbp; Mal1; PAFABP; PA-FABP; PA-FABPepidermal; Psoriasis-associated fatty acid-binding protein homolog
• Host Species: Rat
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 2171
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized