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F4/80 Rat, anti-Mouse, Alexa Fluor 488, Clone: BM8, STEMCELL Technologies

Rat Monoclonal Antibody

£251.10 - £544.05

Specifications

Antigen F4/80
Clone BM8
Applications Immunohistochemistry, Western Blot, ELISA, Flow Cytometry, Immunocytochemistry
Classification Monoclonal
Conjugate Alexa Fluor 488
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17198581
Encompass_Preferred
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Stemcell Technologies
60027AD.1
25 μg
£251.10
25µg
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17188581
Encompass_Preferred
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Stemcell Technologies
60027AD
100 μg
£544.05
100µg
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Description

Description

  • The BM8 antibody reacts with the F4/80 antigen (also termed Ly-71 in mouse and EMR-1 in human), an ∼160 kDa transmembrane glycoprotein belonging to the EGF-TM7 family of G-protein-coupled receptors
  • F4/80 is considered a marker of choice for the identification of mature tissue macrophages, being broadly but variably expressed by this cell type in the liver (Kupffer cells), skin (Langerhans cells), bone marrow stroma, pancreas, thymus, spleen (red pulp), lung, and other tissues
  • It is also expressed by circulating monocytes, eosinophils and a subset of dendritic cells
  • F4/80 is reportedly the only macrophage marker suitable for distinguishing destructive from non-destructive inflammatory processes in the pancreas
  • This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse Monocyte Enrichment Kit (Catalog #19761) and EasySep™ Mouse CD11b Positive Selection Kit (Catalog #18770)
Specifications

Specifications

F4/80
Immunohistochemistry, Western Blot, ELISA, Flow Cytometry, Immunocytochemistry
Alexa Fluor 488
Human, Mouse
Primary
BM8
Monoclonal
Rat
IgG2a κ
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