Invitrogen™ F131C Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA556623

Product Code. 15754531

Description

Immunogen sequence: AEDEHYCCLP DELREARFAA GVAEQFAITE ATLSAWSSLD EEELHPENSP QGIVQLQDLE SIYLQDSLPS G Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 89%.

F131C gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the brain, lungs, and other tissues from oxidative stress. Proteolytic processing of the encoded protein results in the formation of two distinct homotetramers that differ in their ability to interact with the extracellular matrix (ECM). Homotetramers consisting of the intact protein, or type C subunit, exhibit high affinity for heparin and are anchored to the ECM. Homotetramers consisting of a proteolytically cleaved form of the protein, or type A subunit, exhibit low affinity for heparin and do not interact with the ECM. A mutation in this gene may be associated with increased heart disease risk.

Specifications

• Antigen: F131C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FAM131C
• Gene Alias: C1orf117; FAM131C; family with sequence similarity 131 member C; family with sequence similarity 131, member C; Gm693; hypothetical protein LOC619198; protein FAM131C; RP11-5P18.9; zgc:110264
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 348487
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96AQ9
• Gene Symbols: FAM131C
• Immunogen: Recombinant protein corresponding to Human F131C. Recombinant protein control fragment (Product #RP-94504).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG