exo-IWR 1, Tocris Bioscience™

Description

Negative control for endo-IWR 1 25-fold less active than endo-IWR 1; exhibits decreased activity against the Wnt/β-catenin pathway.

Active Analog also available.

Chemical Identifiers

• CAS: 1127442-87-8
• Molecular Weight (g/mol): 409.445
• Synonym: iwr-1-exo, exo-iwr 1, 4-3ar,4r,7s,7as-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2h-4,7-methanoisoindol-2-yl-n-quinolin-8-yl benzamide, exo-iwr-1, 4-3ar,4r,7s,7as-rel-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2h-isoindol-2-yl-n-8-quinolinylbenzamide, rel-4-3ar,4r,7s,7as-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2h-isoindol-2-yl-n-8-quinolinylbenzamide
• ChEBI: CHEBI:62883

• Molecular Formula: C25H19N3O3
• InChI Key: ZGSXEXBYLJIOGF-BTYSMDAFSA-N
• PubChem CID: 1163034
• SMILES: C1C2C=CC1C3C2C(=O)N(C3=O)C4=CC=C(C=C4)C(=O)NC5=CC=CC6=C5N=CC=C6

Specifications

• CAS: 1127442-87-8
• Synonym: iwr-1-exo, exo-iwr 1, 4-3ar,4r,7s,7as-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2h-4,7-methanoisoindol-2-yl-n-quinolin-8-yl benzamide, exo-iwr-1, 4-3ar,4r,7s,7as-rel-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2h-isoindol-2-yl-n-8-quinolinylbenzamide, rel-4-3ar,4r,7s,7as-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2h-isoindol-2-yl-n-8-quinolinylbenzamide
• SMILES: C1C2C=CC1C3C2C(=O)N(C3=O)C4=CC=C(C=C4)C(=O)NC5=CC=CC6=C5N=CC=C6
• PubChem CID: 1163034
• Formula Weight: 409.44
• Chemical Name or Material: exo-IWR 1

• Molecular Formula: C25H19N3O3
• InChI Key: ZGSXEXBYLJIOGF-BTYSMDAFSA-N
• Molecular Weight (g/mol): 409.445
• ChEBI: CHEBI:62883
• Percent Purity: >99%

Safety and Handling

Recommended Storage : Store at Room Temperature