Invitrogen™ ETV6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA590606

Product Code. 16557901

Description

Immunogen sequence: MSETPAQCSI KQERISYTPP ESPVPSYASS TPLHVPVPRA LRMEEDSIRL PAHLRLQPIY WSRDDVAQWL KWAENEFSLR PIDSNTFEMN GKALLLLTKE DFRYRSPHSG DVLYELLQHI LKQRKPRILF SPFFHPGNSI HTQPEVILHQ NHEEDNCVQR TPRPSVDNVH HNPPTIELLH RSRSPITTNH RPSPDPEQRP LRSPLDNMIR RLSPAERAQG PRPHQENNHQ ESYPLSVSPM ENNHCPASSE SHPKPSSPRQ ESTRVIQLMP SPIMHPLILN PRHSVDFKQS RLSEDGLHRE; Positive Samples: HepG2, Mouse lung, Mouse spleen, Rat testis; Cellular Location: Nucleus.

This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and Maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

Specifications

• Antigen: ETV6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Etv6
• Gene Alias: AW123102; AW557856; CGI-108; CSL4; Csl4p; ETS translocation variant 6; ETS variant 6; ets variant gene 6 (TEL oncogene); ETS-related protein Tel1; Etv6; hCsl4p; p13; RP11-452K12.9; SKI4; Ski4p; Tel; TEL/ABL; Tel1; TEL1 oncogene; THC5; Transcription factor ETV6
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14011, 2120, 312777
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.04 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P41212, P97360
• Gene Symbols: Etv6
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ETV6 (NP_0019781).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG