ETV4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10684-1-AP-150UL

Product Code. 16867223

Description

ETV4: ets variant gene 4 (E1A enhancer binding protein, E1AF), also known as PEA3. Several members of the Ets gene family are known to encode sequencespecific DNA binding proteins. These include mouse PU. 1, mouse and human Ets-1, Drosophila E74, chicken and human Ets-2 and rat GABP-a. Each of these proteins recognizes similar motifs in DNA that share a centrally located 5′-GGAA-3′ element. For instance, PEA3 binds the motif 5′-AGGAAG-3′ (the PEA-3 motif), but does not bind to the sequence 5′-AGGAAC-3′, recognized by PU. 1, although PU. 1 binds equally well to both sequences. It appears that all of the Ets proteins recognize the same central core sequence but that each protein interacts with unique sequences that flank this core. PEA3 is expressed at readily detectable levels in cells of epithelial and fibroblastic origin but is not expressed in hematopoietic cells. This is in contrast to other members of the Ets gene family, such as Ets-1, Ets-2 and Fli-1, each of which is expressed primarily in cells of hematopoietic origin.

Specifications

• Antigen: ETV4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ETV4
• Gene Alias: E1A F, E1AF, ETS translocation variant 4, ets variant 4, ETV4, PEA3, PEAS3, Protein PEA3
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18612, 2118, 360635
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.25 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: P28322, P43268
• Gene Symbols: Etv4
• Immunogen: ETV4 Fusion Protein Ag0984
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG