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Epiberberine chloride, MedChemExpress

Product Code. 16411348
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Quantity:
5 mg
10 mg
Unit Size:
10mg
5mg
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Product Code. 16411348

Brand: Medchem Express HYN0226A

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Description

MedChemExpress Epiberberine chloride is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BACE1 inhibitor, with IC50s of 1.07, 6.03 and 8.55 μM, respectively.

Epiberberine chloride has antioxidant activity, with peroxynitrite ONOO- scavenging effect (IC50, 16.83 μM), and may protect against Alzheimer disease. Epiberberine chloride inhibits the early stage of differentiation of 3T3-L1 preadipocytes, downregulates the Raf/MEK1/2/ERK1/2 and AMPKα/Akt pathways. Epiberberine has the potential effect in the research of diabetic disease.

Specifications

Chemical Name or Material Epiberberine chloride
CAS 889665-86-5
Color Yellow
Purity Grade Notes Research
Molecular Formula C20H18ClNO4
Quantity 5 mg
Solubility Information DMSO : 25 mg/mL (67.24 mM; Need ultrasonic)
SMILES COC1=C(OC)C=C2C(CC[N+]3=C2C=C(C=C4)C(C5=C4OCO5)=C3)=C1.[Cl-]
Molecular Weight (g/mol) 371.81
Formula Weight 371.81
Percent Purity 98.89%
Grade Research
Physical Form Solid
For Use With (Application) Metabolism-sugar/lipid metabolism
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Research purposes only

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