Ethyl 2-methylacetoacetate, 95%, Thermo Scientific Chemicals

Description

Ethyl 2-methylacetoacetate is used in Japp-Klingemann reaction to prepare hydrazones from beta-keto acid and aryl diazonium salts. It is used as a precursor involved in the synthesis of ethylpyruvate phenylhydrazone via reaction with benzenediazonium chloride.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ethyl 2-methylacetoacetate is used in Japp-Klingemann reaction to prepare hydrazones from beta-keto acid and aryl diazonium salts. It is used as a precursor involved in the synthesis of ethylpyruvate phenylhydrazone via reaction with benzenediazonium chloride.

Solubility
Miscible with alcohol and ether. Silghtly miscible with water.

Notes
Incompatible with strong oxidizing agents and strong bases.

Specifications

Chemical Identifiers

• CAS: 609-14-3
• Molecular Formula: C7H12O3
• Molecular Weight (g/mol): 144.17
• MDL Number: MFCD00009164
• InChI Key: FNENWZWNOPCZGK-UHFFFAOYSA-N
• Synonym: ethyl 2-methylacetoacetate, ethyl 2-acetylpropionate, ethyl-2-methyl acetoacetate, ethyl methylacetoacetate, ethyl 2-methyl-3-oxobutyrate, ethyl2-methylacetoacetate, butanoic acid, 2-methyl-3-oxo-, ethyl ester, 2-methylacetoacetic acid ethyl ester, ethyl alpha-methylacetylacetate, 2-methyl-3-oxobutanoic acid ethyl ester
• PubChem CID: 701
• IUPAC Name: ethyl 2-methyl-3-oxobutanoate
• SMILES: CCOC(=O)C(C)C(=O)C

• Melting Point: -45°C
• Density: 1.019
• Boiling Point: 185°C
• Flash Point: 62°C (143°F)
• Odor: Ester-like
• Refractive Index: 1.418
• Quantity: 25 g
• Beilstein: 1071742
• Solubility Information: Miscible with alcohol and ether. Silghtly miscible with water.
• Formula Weight: 144.17
• Percent Purity: 95%
• Chemical Name or Material: Ethyl 2-methylacetoacetate

RUO – Research Use Only