Invitrogen™ ETFA Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA530021

Product Code. 13454457

Description

Recommended positive controls: 293T, A431, HeLa, HepG2, C8D30, PC-12. Predicted reactivity: Mouse (96%), Rat (95%), Zebrafish (84%), Xenopus laevis (85%), Cat (96%), Pig (96%), Chicken (87%), Rhesus Monkey (98%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: ETFA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ETFA
• Gene Alias: 2010200I21Rik; Alpha-ETF; D9Ertd394e; electron transfer flavoprotein alpha subunit; electron transfer flavoprotein alpha-subunit; electron transfer flavoprotein subunit alpha, mitochondrial; electron transfer flavoprotein, alpha polypeptide; electron transferring flavoprotein, alpha polypeptide; electron-transfer-flavoprotein alpha polypeptide; electron-transfer-flavoprotein, alpha polypeptide; EMA; ETF; ETFA; GA2; glutaric aciduria II; MADD
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 110842, 2108, 300726
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 0.91 mg/mL
• Formulation: PBS with 20% glycerol; pH 7
• Gene Accession No.: P13803, P13804, Q99LC5
• Gene Symbols: ETFA
• Immunogen: Recombinant protein encompassing a sequence within the center region of human ETFA. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG