Invitrogen™ UBE2D1 Recombinant Rabbit Monoclonal Antibody (24GB1900)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA557304

Product Code. 30275788

Beskrivning

UBE2D1 Recombinant Monoclonal Antibody for Western Blot, Flow

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.

Specifikationer

• Antigen: UBE2D1
• Classification: Recombinant Monoclonal
• Conjugate: Unconjugated
• Gene: UBE2D1
• Gene Alias: (E3-independent) E2 ubiquitin-conjugating enzyme D1; E2 ubiquitin-conjugating enzyme D1; E2(17)KB 1; E2(17)KB1; SFT; Stimulator of Fe transport; UBC 4/5; UBC4/5; UBC4/5 homolog; UBC5A; UBCH 5; UBCH 5A; UBCH5; UBCH5A; UBE2D1; ubiquitin; Ubiquitin carrier protein D1; ubiquitin conjugating enzyme E2 D1; ubiquitin conjugating enzyme E2D 1; ubiquitin-conjugating enzyme E2 D1; Ubiquitin-conjugating enzyme E2(17)KB 1; ubiquitin-conjugating enzyme E2-17 kDa 1; ubiquitin-conjugating enzyme E2D 1; ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2D 1, UBC4/5 homolog; ubiquitin-protein ligase D1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 216080, 361831, 7321
• Content And Storage: -20°C
• Form: Liquid

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 24GB1900
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: D3ZDK2, P51668, P61080
• Gene Symbols: UBE2D1
• Immunogen: A synthesized peptide derived from human UBE2D1 (aa 110-147).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG