ESR1 Mouse anti-Human, Rat, Clone:6A6E8, Abnova™

Mouse monoclonal antibody raised against recombinant human ESR1.

Brand:  Abnova MAB17277.100ug

Product Code. 16064716

Description

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5′ UTRs and use different promoters. [provided by RefSeq]

Specifications

• Antigen: ESR1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Immunohistochemistry (1:200-1:1000)
  Immunocytochemistry (1:200-1:1000)
  Flow Cytometry (1:200-1:400)
  The optimal working dilution should be determined by the end user.
• Gene: ESR1
• Host Species: Mouse
• Quantity: 100 μg
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 6A6E8
• Description: estrogen receptor 1
• Formulation: In PBS (0.05% sodium azide)
• Gene Alias: DKFZp686N23123, ER, ESR, ESRA, Era, NR3A1
• Immunogen: Recombinant protein corresponding to amino acid 2-185 of human ESR1 from E. coli.
• Gene ID (Entrez): 2099
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid