Invitrogen™ ERRF Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA534534

Product Code. 15335461

Description

A suggested positive control is Hela cell lysate. PA5-34534 can be used with blocking peptide PEP-1577.

The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.

Specifications

• Antigen: ERRF
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SRARP
• Gene Alias: C1orf64; chromosome 1 open reading frame 64; ER-related factor; ERRF; Gm694; predicted gene 694; RP11-5P18.4; Srarp; SSPR; Steroid receptor-associated and regulated protein; Steroid receptor-regulated protein; uncharacterized protein C1orf64; uncharacterized protein C1orf64 homolog
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 149563, 277744
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q8NEQ6
• Gene Symbols: SRARP
• Immunogen: A 15 amino acid peptide near the carboxy terminus of human ERRF.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG