missing translation for 'onlineSavingsMsg'
Learn More

Invitrogen™ ERLIN2 Monoclonal Antibody (C2), Invitrogen™

Mouse Monoclonal Antibody

£178.00 - £408.00

Specifications

Antigen	ERLIN2
Clone	C2
Concentration	1 mg/mL
Applications	Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification	Monoclonal

View More Specs

Products 2

Product Code	Brand	Quantity	Price	Quantity & Availability
Product Code	Brand	Quantity	Price	Quantity & Availability
17694286 View Documents missing translation for 'viewProductCertificates'	Invitrogen™ MA543835	20 μL	£178.00 20µL View alternative products Save Up to »		Please sign in to purchase this item. Need a web account? Register with us today!

17684286 View Documents missing translation for 'viewProductCertificates'	Invitrogen™ MA543834	100 μL	£408.00 100µL View alternative products Save Up to »		Please sign in to purchase this item. Need a web account? Register with us today!

Description

ERLIN2, also named as C8orf2 and SPFH2, is a component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1, 4, 5-trisphosphate receptors (IP3Rs) such as ITPR1. It promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. ERLIN2 is involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. The MW of ERLIN1/ERLIN2 complex is about 70 kDa.

Specifications

Antigen	ERLIN2
Concentration	1 mg/mL
Classification	Monoclonal
Form	Liquid
Regulatory Status	RUO
Formulation	PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene Alias	BC036333; C87251; C8orf2; EMBL:AAI68668.1, ECO:0000312; EMBL:AAI68668.1}; endoplasmic reticulum lipid raft-associated protein 2; endoplasmic reticulum lipid raft-associated protein 2 {ECO:0000250; ER lipid raft associated 2; Erlin2; erlin-2; erlin-2 {ECO:0000250; erlin2 {ECO:0000312; HGNC:1356; MGC87072; NET32; RGD:1309010}; RGD1309010; SPFH domain family, member 2; SPFH domain-containing protein 2; SPFH domain-containing protein 2 {ECO:0000250; Spfh2; SPG18; stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2; stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2 {ECO:0000250; UniProtKB:Q8BFZ9, ECO:0000312; UniProtKB:Q8BFZ9}; UNQ2441; UNQ2441/PRO5003/PRO9924
Gene Symbols	ERLIN2
Isotype	IgG2a λ
Purification Method	Protein A/G
Product Type	Antibody

Clone	C2
Applications	Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Conjugate	Unconjugated
Host Species	Mouse
Target Species	Human
Gene Accession No.	O94905
Gene ID (Entrez)	11160
Immunogen	Pro47-Asn339 (Accession O94905), with N-terminal His Tag.
Primary or Secondary	Primary
Content And Storage	Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene	ERLIN2

Spot an opportunity for improvement?Share a Content Correction

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

Your Name

Email Address *

Type of Issue *

Detailed Description of Issue/Request *

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.

Invitrogen™ ERLIN2 Monoclonal Antibody (C2), Invitrogen™

Specifications

Description

Specifications

Documents