Invitrogen™ ERAS Monoclonal Antibody (D10-B9)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA532907

Product Code. 16366314

Description

ERAS Monoclonal Antibody for ICC/IF, IHC (P)

The human ERAS gene was initially reported as a processed pseudogene (HRasp, Ha-Ras2), with several base substitutions in coding regions, but was more recently described as potentially encoding a functional human ERAS protein. The ERAS oncogene supports the tumorigenic growth of embryonic stem cells by producing a constitutively active Ras protein. ERAS protein has less than 50% amino acid identity with H-Ras, another member of Ras family but the key domains essential for Ras function are highly conserved. The protein also contains amino-acid residues identical to those present in active mutants of Ras and causes oncogenic transformation in NIH 3T3 cells. Human ERAS gene is localized in the chromosomal region Xp11.23.

Specifications

• Antigen: ERAS
• Classification: Monoclonal
• Concentration: 2 mg/mL
• Formulation: PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q7Z444
• Gene Symbols: ERAS
• Immunogen: Recombinant protein within Human ERAS aa 1-233.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry, Immunohistochemistry
• Clone: D10-B9
• Conjugate: Unconjugated
• Gene: ERAS
• Gene Alias: ecat5; Embryonic stem cell-expressed Ras; ERAS; E-Ras; ES cell expressed Ras; ES cell-expressed Ras; GTPase ERas; Ha-Ras2; HRAS2; HRasp; small GTPase E-Ras; small GTPase protein E-Ras; v-Ha-ras Harvey rat sarcoma viral oncogene homolog 2; v-Ha-ras Harvey rat sarcoma viral oncogene homolog pseudogene
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3266
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid