Invitrogen™ EPS15 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA597253

Product Code. 16590082

Description

Immunogen sequence: RQSTDPFATS STDPFSAANN SSITSVETLK HNDPFAPGGT VVAASDSATD PFASVFGNES FGGGFADFST LSKVNNEDPF RSATSSSVSN VVITKNVFEE TSVKSEDEPP ALPPKIGTPT RPCPLPPGKR SINKLDSPDP FKLNDPFQPF PGNDSPKEKD PEIFCDPFTS ATTTTNKEAD P; Positive Samples: HeLa, Jurkat, 293T, NIH/3T3, Mouse liver, Mouse spleen, Mouse lung; Cellular Location: Cell membrane, Cytoplasm, Cytoplasmic side, Early endosome membrane, Membrane, Peripheral membrane protein, clathrin-coated pit.

EPS15 is a ubiquitously expressed protein that is involved in cell growth regulation and may be involved in the regulation of mitogenic signals and control of cell proliferation. Phosphorylation of EPS15 on Tyrosine 849 upon DNA damage is involved in the internalization of EGFR. A chromosomal aberration involving EPS15 is also found in acute leukemias, resulting in a rogue activator protein.

Specifications

• Antigen: EPS15
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPS15
• Gene Alias: 2410112D09Rik; AF1P; AF-1P; AF-1p protein; ALL1 fused gene from chromosome 1; epidermal growth factor pathway substrate 15; epidermal growth factor receptor pathway substrate 15; epidermal growth factor receptor substrate 15; EPS15; MLLT5; protein AF-1p; Protein Eps15; RGD1307641
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13858, 2060, 313474
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.82 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P42566, P42567
• Gene Symbols: EPS15
• Immunogen: Recombinant protein (or fragment).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG