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Invitrogen™ EpoR Polyclonal Antibody

Product Code. 16364745 Shop All Thermo Scientific Products
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Quantity:
100 μg
Unit Size:
100µg
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16364745 100 μg 100µg
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Product Code. 16364745 Supplier Invitrogen™ Supplier No. PA595480

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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: rat lung tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

EpoR encodes the erythropoietin receptor, which belongs to the cytokine receptor family. When erythropoietin binds to this receptor, it activates the Jak2 tyrosine kinase, which in turn activates various intracellular pathways including Ras/MAP kinase, phosphatidylinositol 3-kinase, and STAT transcription factors. The stimulated erythropoietin receptor plays a role in the survival of erythroid cells. Defects in this gene may result in erythroleukemia and familial erythrocytosis. Dysregulation of this gene may also affect the growth of certain tumors. Multiple transcript variants are produced as a result of alternate splicing. Diseases associated with EPOR include Erythrocytosis, Familial, 1 and Erythroleukemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EpoR
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene EPOR
Gene Accession No. P14753, P19235, Q07303
Gene Alias EPO R; EPOR; EPO-R; Erythropoietin receptor; pEpoR
Gene Symbols EPOR
Host Species Rabbit
Immunogen E.coli-derived human EPO Receptor recombinant protein (Position: E48-E226).
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13857, 2057, 24336
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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