Invitrogen™ Epiregulin Monoclonal Antibody (183625)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA560980

Product Code. 30536246

Description

Reconstitute at 0.5 mg/mL in sterile PBS.

Epiregulin is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes, as well as in certain carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. It also inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence.

Specifications

• Antigen: Epiregulin
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with trehalose and no preservative
• Gene Accession No.: O14944
• Gene Symbols: Ereg
• Immunogen: E. coli-derived recombinant human Epiregulin, Val63-Leu108.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: 183625
• Conjugate: Unconjugated
• Gene: Ereg
• Gene Alias: Ep; Epiregulin; EPR; ER; EREG; Proepiregulin
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 2069
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized