Invitrogen™ EphB6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Marca:  Invitrogen™ PA5120289

Codice prodotto. 17791684

Descrizione

Positive test controls include: U-251MG, BxPC-3, Mouse thymus, Mouse brain. The target is usually found in the following locations: Membrane, Secreted, Single-pass type I membrane protein. Immunogen sequence: HFDQLVAAFD KMIRKPDTLQ AGGDPGERPS QALLTPVALD FPCLDSPQAW LSAIGLECYQ DNFSKFGLCT FSDVAQLSLE DLPALGITLA GHQKKLLHHI QLLQQHLRQQ GSVEV.

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.

Specifica

• Antigen: EphB6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPHB6
• Gene Alias: Cekl; chicken eph/elk receptor-like protein; EPB6; EPH receptor B6; EPHB6; EphB6v; Epherin B6; Epherin receptor B6; ephrin type A receptor; ephrin type-B receptor 6; HEP; human kinase-defective Eph-family receptor protein; MEP; MGC129910; MGC129911; Tyrosine-protein kinase-defective receptor EPH-6
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13848, 2051
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.51 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O08644, O15197
• Gene Symbols: EPHB6
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 615-729 of human EPHB6 (NP_001267724.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG