EphB1/EphB2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA538481

Product Code. 15575401

Description

The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. While the biological activities of these receptors have yet to be determined, there is increasing evidence that they are involved in central nervous system function and in development. The Eph subfamily receptors of human origin (and their murine/avian homologs) include EphA1(Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12),EphA7 (Hek11/MDK1), EphA8 (Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3(Cek10, Hek2), EphB4 (Htk), EphB5 (Hek9) and EphB6 (Mep). Ligands for Eph receptors include ephrin-A4 (LERK-4) which binds EphA3 and EphB1. In addition, Ephrin-A2 (Elf-1) has been described as the ligand for EphA4, ephrin-A3 (Ehk1-L) as the ligand for EphA5 and ephrin-B2 (Htk-L) as the ligand for EphB4 (Htk).

Specifications

• Antigen: EphB1/EphB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPHB1
• Gene Alias: ETK2; HEK2; TYRO6; EPHB3, DRT; ERK; CAPB; Hek5; PCBC; EPHT3; Tyro5; MGC87492; EPHB2, Ephrin type-B receptor 1; Tyrosine-protein kinase receptor EPH-2; NET, HEK-6, ELK, Ephrin type-B receptor 2, Ephrin B1, EphrinB1, Ephrin B2, EphrinB2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13844, 2047, 2048, 24338, 270190, 313633
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P29323, P54762, P54763, Q8CBF3, P09759
• Gene Symbols: EPHB1, EPHB2
• Immunogen: A synthetic non-phosphopeptide derived from human EPHB1/2 around the phosphorylation site of tyrosine594/604 (K-I-YP-I-D)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG