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Eurofins DiscoverX EphA5 Protein, Active
Beschreibung
Eph (erythropoietin-producing hepatocellular) family tyrosine kinase receptors consist of two groups: EphA group members respond to ephrin-A, which is anchored to the cell membrane by glycosylphosphatidylinositol, whereas EphB group members respond to ephrin-B, containing a transmembrane domain. Among them, only EphA4 can cross-respond to both ephrin-A and -B. EphA5 (EHK1, HEK7, CEK7, TYRO4) is widely distributed in CNS. The localization of EphA5 to motor and sensory neurons is consistent with a role of EphA5 in neural plasticity, cell–cell recognition, and topographical orientation of neuronal systems.
GenBank NM_004439
Spezifikation
Spezifikation
| Formulation | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
| Molecular Weight (g/mol) | 37.9 kDa |
| Quantity | 10 μg |
| Species | Human |
| Recombinant | Recombinant |
| Protein Tag | N-terminal 6His |
| Expression System | Recombinant enzyme expressed in Sf21 insect cells |
| Protein Form | Truncated |
| Purity or Quality Grade | ≥77% |
| Protein | EphA5, active |
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