EpCAM/TROP1 Antibody (MOC-31) - IHC-Prediluted, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-48287

Product Code. 18109598

Beskrivning

EpCAM/TROP1 Monoclonal specifically detects EpCAM/TROP1 in Human, Rat (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifikationer

• Antigen: EpCAM/TROP1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Symbols: EPCAM
• Immunogen: Neuraminidase treated GLS-1 human small cell lung carcinoma cells
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Binding epitope of this antibody is located in the first EGF-like repeat domain (EGF1) between amino acids 27-59 of Ep-CAM.EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas with the exception of adult squamous epithelium, hepatocytes and gastric epithelial cells. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ

• Applications: Immunohistochemistry (Paraffin)
• Clone: MOC-31
• Dilution: Immunohistochemistry-Paraffin
• Gene Alias: 17-1A, 323/A3, ACSTD1, antigen identified by monoclonal AUA1, CD326 antigen, Cell surface glycoprotein Trop-1, chromosome 4, surface marker (35kD glycoprotein), DIAR5, EGP, EGP-2, EGP314, EGP40, EpCAM, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2EGP34, hEGP314, HNPCC8, KS 1/4 antigen, KS1/4, KSAHEA125, M1S2, M4S1Ly74, Major gastrointestinal tumor-associated protein GA733-2, MIC18MH99, MOC31, TACST-1, TACSTD1, TROP1CD326, Tumor-associated calcium signal transducer 1CO-17A
• Host Species: Mouse
• Molecular Weight of Antigen: 41 kDa
• Quantity: 7 mL
• Research Discipline: Cancer, Cancer Stem Cells, Tumor Biomarkers
• Gene ID (Entrez): 4072
• Target Species: Human, Rat (Negative)
• Form: Purified