Invitrogen™ EPB41 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA596134

Product Code. 16588971

Description

Immunogen sequence: MHCKVSLLDD TVYECVVEKH AKGQDLLKRV CEHLNLLEED YFGLAIWDNA TSKTWLDSAK EIKKQVRGVP WNFTFNVKFY PPDPAQLTED ITRYYLCLQL RQDIVAGRLP CSFATLALLG SYTIQSELGD YDPELHGVDY VSDFKLAPNQ TKELEEKVME LHKSYRSMTP AQADLEFLEN AKKLSMYGVD LHKAKDLEGV DIILGVCSSG LLVYKDKLRI NRFPWPKVLK ISYKRSSFFI KIRPGEQEQY ESTIGFKLPS YRAAKKLWKV CVEHHTFFRL TSTDTIPKSK F; Positive Samples: 293T, Mouse brain, Mouse liver; Cellular Location: Cytoplasm, Nucleus, cell cortex, cytoskeleton.

Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4. 1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene, the beta-spectrin gene, or the band 3 gene.

Specifications

• Antigen: EPB41
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPB41
• Gene Alias: 4.1R; AI415518; Band 4.1; D4Ertd442e; E41P; EL1; elliptocytosis 1, RH-linked; Elp1; Elp-1; EPB4.1; EPB41; erythrocyte membrane protein band 4.1; erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked); erythrocyte protein band 4.1; erythrocyte skeletal protein; erythrocyte surface protein band 4.1; HE; Kiaa4056; mKIAA4056; P4.1; protein 4.1; Protein 4.1R; RGD1564762
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2035, 269587
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.18 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P11171, P48193
• Gene Symbols: EPB41
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 210-500 of human EPB41 (NP_0011594781).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG