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Entrectinib, MedChemExpress
MedChemExpress Entrectinib (NMS-E628) is a potent, orally available, and CNS-active pan-Trk, ROS1, and ALK inhibitor. Entrectinib inhibits TrkA, TrkB, TrkC, ROS1 and ALK with IC50 values of 1, 3, 5, 12 and 7 nM, respectively. Antitumor activity.
£79.86 - £435.60
Specifications
| Chemical Name or Material | Entrectinib |
|---|---|
| CAS | 1108743-60-7 |
| Color | Off-White |
| Purity Grade Notes | Research |
| Molecular Formula | C31H34F2N6O2 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16497997
|
Medchem Express
HY-12678 |
5 mg |
£79.86
5mg |
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|
16455946
|
Medchem Express
HY-12678 |
100 mg |
£435.60
100mg |
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|
16435288
|
Medchem Express
HY-12678 |
10 mg |
£118.58
10mg |
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|
16401497
|
Medchem Express
HY-12678 |
50 mg |
£251.68
50mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Entrectinib (NMS-E628) is a potent, orally available, and CNS-active pan-Trk, ROS1, and ALK inhibitor. Entrectinib inhibits TrkA, TrkB, TrkC, ROS1 and ALK with IC50 values of 1, 3, 5, 12 and 7 nM, respectively. Antitumor activity.Specifications
| Entrectinib | |
| Off-White | |
| C31H34F2N6O2 | |
| DMSO : ≥ 31 mg/mL (55.29 mM) | |
| 560.64 | |
| 98.13% | |
| Solid |
| 1108743-60-7 | |
| Research | |
| NMS-E628 RXDX-101 | |
| O=C(NC1=NNC2=C1C=C(CC3=CC(F)=CC(F)=C3)C=C2)C4=C(NC5CCOCC5)C=C(N6CCN(C)CC6)C=C4 | |
| 560.64 | |
| Research | |
| Cancer-Kinase/protease |
Safety and Handling
H302∣H315∣H319∣H335
missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Research purposes only
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