Endoglin/CD105 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16857533	Proteintech 10862-1-AP-20UL	20 μL
16847533	Proteintech 10862-1-AP-150UL	150 μL

Description

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.

Specifications

• Antigen: Endoglin/CD105
• Applications: Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Mouse, Rat, Human
• Gene Accession No.: P17813, Q63961
• Gene ID (Entrez): 13805, 2022, 497010
• Immunogen: Endoglin/CD105 Fusion Protein Ag1287
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: ENG

• Concentration: 0.25 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: CD105, END, Endoglin, ENG, HHT1, ORW, ORW1
• Gene Symbols: Eng
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody