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  5. Tocris Bioscience™ EMD 386088 hydrochloride

Tocris Bioscience™ EMD 386088 hydrochloride
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Product Code. 18726026
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18726026 10 mg 10mg
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Product Code. 18726026 Supplier Tocris Bioscience™ Supplier No. 2382/10

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Description

Potent 5-HT6 agonist

EMD 386088 hydrochloride is a potent 5-HT6 receptor agonist (EC50 = 1.0 nM) that displays selectivity over other 5-HT receptors (IC50 values are 7.4, 110, 180, 240, 450, 620, 660 and 3000 nM for 5-HT6, 5-HT1D, 5-HT1B, 5-HT2A, 5-HT2C, 5-HT4, 5-HT1A and 5-HT7 receptors respectively). Shows moderate affinity at 5-HT3 receptors (IC50 = 34 nM).
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Specifications

Chemical Name or Material 5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole hydrochloride
CAS 1171123-46-8
Assay Percent Range >99%
Quantity 10 mg
Solubility Soluble to 100mM in DMSO
Molecular Formula C14H15N2Cl.HCl
Formula Weight Observed MW: 283.2

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