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Embigin, clone: G7.43.1, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-5839-81

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15297497

  • £69.05 / 50µg


Estimated Shipment
30-10-2018
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Description

Description

Description: This G7.43.1 monoclonal antibody reacts with mouse embigin (gp70), a single transmembrane glycoprotein that is a member of the Ig superfamily similar to basigin and EMMPRIN. It contains two Ig domains thought to be involved in cellular adhesion and tissue remodeling. Expression of embigin is high before day 10 in fetal development. In the adult it is expressed on myeloid cells and T cells but not B cells. During hematopoeisis, embigin is expressed on HSCs and CLPs (common lymphoid progenitors) but absent on pro- and pre-B cells. In recent studies Pax 5 has been shown to repress embigin expression.Applications Reported: This G7.43.1 antibody has been reported for use in flow cytometric analysis and immunohistology staining of frozen tissue sections.Applications Tested: This G7.43.1 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

Embigin
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
P21995
embigin homolog
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow Cytometry, Immunohistochemistry (Frozen)
G7.43.1
Unconjugated
Emb
Liquid
Emb
IgG2b, kappa, kappa
50μg
4° C
Primary
13723
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