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Invitrogen™ ELOVL7 Polyclonal Antibody
Description
A suggested positive control is human liver tissue lysate. PA5-20913 can be used with blocking peptide PEP-1027.
Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 7 (ELOVL7) is a member of fatty acyl-CoA elongase gene family that elongates saturated very-long-chain fatty acids (SVLFA, C20:0-) and has been suggested to be involved in prostate cancer growth through saturated long-chain fatty acid metabolism. The metabolic pathways of long-chain fatty acids play an important role in the maintenance of membrane lipid composition and the generation of cell signaling precursor molecules such as eicosanoids and sphingosine-1 phosphate. Overexpression of ELOVL7 results in lipid accumulation in differentiated adipocytes; its expression is regulated by the microRNA miR-219.
Specifications
Specifications
| Antigen | ELOVL7 |
| Applications | Immunohistochemistry, Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.02% sodium azide |
| Gene | ELOVL7 |
| Gene Accession No. | A1L3X0, Q9D2Y9 |
| Gene Alias | 3-keto acyl-CoA synthase Elovl7; 9130013K24Rik; AI840082; elongation of very long chain fatty acids protein 7; elongation of very long chain fatty acids-like 7; ELOVL FA elongase 7; ELOVL family member 7, elongation of long chain fatty acids; ELOVL family member 7, elongation of long chain fatty acids (yeast); ELOVL fatty acid elongase 7; ELOVL7; Very long chain 3-ketoacyl-CoA synthase 7; very long chain 3-oxoacyl-CoA synthase 7; very-long-chain 3-oxoacyl-CoA synthase 7 |
| Gene Symbols | ELOVL7 |
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