ELOVL7 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA520913

Product Code. 12829062

Description

A suggested positive control is human liver tissue lysate. PA5-20913 can be used with blocking peptide PEP-1027.

Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 7 (ELOVL7) is a member of fatty acyl-CoA elongase gene family that elongates saturated very-long-chain fatty acids (SVLFA, C20:0-) and has been suggested to be involved in prostate cancer growth through saturated long-chain fatty acid metabolism. The metabolic pathways of long-chain fatty acids play an important role in the maintenance of membrane lipid composition and the generation of cell signaling precursor molecules such as eicosanoids and sphingosine-1 phosphate. Overexpression of ELOVL7 results in lipid accumulation in differentiated adipocytes; its expression is regulated by the microRNA miR-219.

Specifications

• Antigen: ELOVL7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ELOVL7
• Gene Alias: 3-keto acyl-CoA synthase Elovl7; 9130013K24Rik; AI840082; elongation of very long chain fatty acids protein 7; elongation of very long chain fatty acids-like 7; ELOVL FA elongase 7; ELOVL family member 7, elongation of long chain fatty acids; ELOVL family member 7, elongation of long chain fatty acids (yeast); ELOVL fatty acid elongase 7; ELOVL7; Very long chain 3-ketoacyl-CoA synthase 7; very long chain 3-oxoacyl-CoA synthase 7; very-long-chain 3-oxoacyl-CoA synthase 7
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 74559, 79993
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: A1L3X0, Q9D2Y9
• Gene Symbols: ELOVL7
• Immunogen: A 15 amino acid peptide near the amino terminus of human ELOVL7.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG