ELOVL6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 21160-1-AP-20UL

Product Code. 16830775

Description

Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.

Specifications

• Antigen: ELOVL6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ELOVL6
• Gene Alias: ELOVL6, FACE, FAE, Fatty acid elongase 2, Fatty acyl CoA elongase, hELO2, LCE, Long chain fatty acyl elongase
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170439, 171402, 79071
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.28 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q920L5, Q920L6, Q9H5J4
• Gene Symbols: Elovl6
• Immunogen: ELOVL6 Fusion Protein Ag14163
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Rat, Human, Mouse
• Product Type: Antibody
• Isotype: IgG