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Invitrogen™ ELOVL6 Polyclonal Antibody

Product Code. 12808702
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12808702 100 μg 100µg
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Product Code. 12808702 Supplier Invitrogen™ Supplier No. PA520520

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human brain tissue lysate. PA5-20520 can be used with blocking peptide PEP-0640.

Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ELOVL6
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ELOVL6
Gene Accession No. Q920L5, Q920L6, Q9H5J4
Gene Alias 3-keto acyl-CoA synthase Elovl6; C77826; Elongation of very long chain fatty acids protein 6; ELOVL FA elongase 6; ELOVL family member 6, elongation of long chain fatty acids; ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast); ELOVL family member 6, elongation of long chain fatty acids (yeast); ELOVL fatty acid elongase 6; ELOVL6; FACE; FAE; fatty acid elongase 2; Fatty acyl-CoA elongase; hELO2; Lce; Lce2; long chain fatty acid elongase; long chain fatty acyl elongase; long-chain fatty-acyl elongase; Masr; Myelin-associated SUR4 protein; rELO2; Very long chain 3-ketoacyl-CoA synthase 6; very long chain 3-oxoacyl-CoA synthase 6; very-long-chain 3-oxoacyl-CoA synthase 6
Gene Symbols ELOVL6
Host Species Rabbit
Immunogen A 15 amino acid peptide near the amino terminus of the human ELOVL6.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 170439, 171402, 79071
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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