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  6. Invitrogen™ ELK1 Recombinant Rabbit Monoclonal Antibody (K01_1Q73)

Invitrogen™ ELK1 Recombinant Rabbit Monoclonal Antibody (K01_1Q73)

Product Code. 30828176
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Quantity:
50 μL
100 μL
Unit Size:
100µL
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30828176 50 μL -
30828420 100 μL 100µL
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Product Code. 30828176 Supplier Invitrogen™ Supplier No. MA564872

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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: PSISVDGLST PVVLSPGPQK P Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%, Pig - 100%, Cynomolgus monkey - 100%.

ELK1 is a component of the ternary complex that binds the serum response element (SRE) and mediates gene activity in response to serum and growth factors. ELK1 is phosphorylated by MAP kinase pathways at a cluster of S/T motifs at its C-terminus. Phosphorylation at these sites, particularly Ser383, is critical for transcriptional activation by ELK1. ELK1 appears to be a direct target of activated MAP kinase. Biochemical studies indicate that ELK1 is a good substrate for MAP kinase, the kinetics of ELK1 phosphorylation and activation correlate with MAP kinase activity, and interfering mutants of MAP kinase block ELK1 activation in vivo. ELK1 is a nuclear target for the ras-raf-MAPK signaling cascade. Alternatively spliced transcript variants encoding the same protein have been found for ELK1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ELK1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone K01_1Q73
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 150mM NaCl, 40% glycerol, 0.05% BSA and 0.01% sodium azide; pH 7.4
Gene ELK1
Gene Accession No. P19419
Gene Alias ELK 1; ELK1; Elk-1; ELK1, ETS transcription factor; ELK1, member of ETS oncogene family; ETS domain-containing protein Elk-1; ETS transcription factor ELK1; ETS-like gene 1; Oncogene Elk1; tyrosine kinase (ELK1) oncogene
Gene Symbols ELK1
Host Species Rabbit
Immunogen A synthetic peptide of human ELK1 (aa 408-428).
Purification Method Protein A/G
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2002
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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